- Naltrexone (Naltima) 50mg tab, 50-150mg/d,
- Acamprosate 2gms/d.
- Disulfiram 250mg Tab. 800mg 1st day, then 600 - 400 - then 100-200 once daily.
Not proven :
. Varenicline (Nicotine receptor agonist)
. Ondansetron (serotinine antogonist)
. Prazocin (alpha-adrenergic agonist)
. Baclofen (GABA B-receptor agonist)
. Topiramate (Anticonvulsant)